RT-06 PLANNING OF BORON NEUTRON CAPTURE THERAPY (BNCT) USING POSITRON EMISSION TOMOGRAPHY (PET)
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چکیده
منابع مشابه
Positron Emission Tomography-based Boron Neutron Capture Therapy Using Boronophenylalanine for High-Grade Gliomas: Part
Based on pharmacokinetic findings of fluorine-18labeled L-fluoroboronophenylalanine by positron emission tomography (PET), methods for estimating tumor iOB concentration were devised. In clinical practice of boron neutron capture therapy (BNCT) for high-grade gliomas, a large amount of L-boronophenylalanine (L iOB BPA)-fructose solution is used. Under these conditions, a slow i.v. infusion of L...
متن کاملPositron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part I.
Determination of tumor boron-10 (10B) levels is required for accurate neutron dosimetry during boron neutron capture therapy. We assessed a new method for quantitative measurement of boronated drug uptake in high-grade gliomas. This method uses positron emission tomography (PET) with fluorine-18-labeled L-fluoroborono-phenylalanine (L-18F-10B-FBPA), which was synthesized as an analogue of L-bor...
متن کاملInvestigation the potential of Boron neutron capture therapy (BNCT) to treat the lung cancer
Introduction: Boron neutron capture therapy (BNCT) is recommended to treat the glioblastoma tumor. It is well known that neuron beams are more effective treatment than photon beams to treat hypoxia tumors due to interaction of neutron with nucleus and production of heavy particles such as 7Li and alpha particle. In this study to evaluate the suitability of BNCT for treating of ...
متن کاملشبیه سازی چشمه 7li(p,n)7be جهت استفاده در bnct (boron neutron capture therapy)
با توجه به اینکه امروزه بیماران بسیاری در سراسر جهان از سرطان رنج میبرند،دانشمندان در تلاشند روشهای درمانی جدیدتر و بهتری را کشف کنند .یکی از این روشها "درمان بوسیله گیراندازی نوترون توسط بور (bnct)" نام دارد که میتواند یکی از بهترین روشهای مفید و موثر و جایگزین در درمان سرطانهایی از نوع glioblastoma و melanoma نسبت به روشهای متداولی چون شیمی درمانی یا رادیوتراپی باشد.در این روش هدف انجام واکنش...
Boron Neutron Capture Therapy Treatment Planning Improvements
The Boron Neutron Capture Therapy (BNCT) treatment planning process of the Harvard/MIT team used for their clinical Phase I trials is very time consuming. If BNCT proves to be a successful treatment, this process must be made more efficient. Since the Monte Carlo treatment planning calculations were the most time consuming aspect of the treatment planning process, requiring more than thirty six...
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ژورنال
عنوان ژورنال: Neuro-Oncology Advances
سال: 2019
ISSN: 2632-2498
DOI: 10.1093/noajnl/vdz039.097